Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Monoamine Transporter - Paroxetine hydrochloride

Paroxetine hydrochloride

CAS No. 78246-49-8

Paroxetine hydrochloride( BRL29060 hydrochloride | BRL29060A )

Catalog No. M15951 CAS No. 78246-49-8

An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class; also shows to be a selective inhibitor of GRK2 activity both in vitro and in living cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 27 In Stock
25MG 41 In Stock
50MG 49 In Stock
100MG 70 In Stock
200MG 101 In Stock
500MG 138 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Paroxetine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class; also shows to be a selective inhibitor of GRK2 activity both in vitro and in living cells.
  • Description
    An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class; also shows to be a selective inhibitor of GRK2 activity both in vitro and in living cells; induce autophagy dependent-NLRP3-inflammasome inhibition in Major depressive disorder.Depression Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BRL29060 hydrochloride | BRL29060A
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Monoamine Transporter
  • Recptor
    5-HT|AChR|GRK2
  • Research Area
    Neurological Disease
  • Indication
    Depression

Chemical Information

  • CAS Number
    78246-49-8
  • Formula Weight
    365.8264
  • Molecular Formula
    C19H21ClFNO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 250 mg/mL; H2O: 2.12 mg/mL
  • SMILES
    C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl
  • Chemical Name
    Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride (1:1), (3S,4R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Thal DM, et al. ACS Chem Biol. 2012 Nov 16;7(11):1830-9. 2. Gassen NC, et al. Autophagy. 2015;11(3):578-80. 3. Alcocer-Gómez E, et al. Pharmacol Res. 2017 Jul;121:114-121.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Vanoxerine

    Vanoxerine (GBR-12909, I-893, Boxeprazine) is a highly potent inhibitor of dopamine uptake in vitro in tissue slices obtained from rat neostriatum with IC50 of 40-50 nM.

  • Rose Bengal

    Rose Bengal is a potent inhibitor of VGlut and vesicular monoamine transporter (VMAT) (Ki of 19 and 64 nM for VGlut andVMAT respectively).

  • Ampreloxetine

    Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively.

Sign In Join Free